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Digestive Glands

I. Liver
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Slide 1: Low power, pig liver. In this animal the hepatic lobules are surrounded by a significant amount of connective tissue. The separation seen here is some what exaggerated due to a shrinkage artifact. Note central veins and portal spaces. The zonation of staining within a lobule is very evident. What might be the cause of this zonation? (Answer: 02 and nutrient availability, etc.)