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Skin

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Slide 1: Thick skin, e=epidermis, arrowhead indicates a ridge of the surface (which gives a fingertip its fingerprint), d=dermis, sc=subcutaneous tissue, arrowhead=papillary ridge.  

Slide 2: Thick skin with sweat gland duct entering rete ridge, stratum corneum, granulosum etc. Note clear basal cells, H&E, Plastic embedded. Section, Monkey.  

Slide 3: Very thick skin. Note the very thick corneum. Arrow points to the stratum lucidum (grey colored layer between the stratum corneum and the stratum granulosum).  

Slide 4: Epidermis. Plastic embedded. Note the intercellular bridges of the stratum spinosum. Clear cells in the basal can be? (Answer: melanocytes, Langerhans or Merkel cells. Human plantar skin.  

Slide 5: Thin skin of breast. Note basal cells and melanocytes in epidermis.  

Slide 6: Slide 6. Skin of hypodermal finger (thick). Line demarcates approximate dermal- junction. Note Pacinian corpuscle (large top arrow) and sweat glands (small bottom arrow).  

Slide 7: Slide 7. Scalp (human). Note demarcation of reticular and papillary layers of dermis. Papillary layer interdigitates with basal surface of epithelium; may contain Meissner's corpuscles. Reticular layer is the major portion of the dermis and is composed of dense bundles of collagen fibers and thick elastic fibers; may contain Pacinian corpuscles.  

Slide 8: Verhoff's stain for elastic fibers in the dermis.  

Slide 9: Longitudinal and oblique sections of hair. h=hair, x=oblique sections, f=follicle, s=sebaceous glands, m-arrector pili muscle.  

Slide 10: Hair bulb. Note: matrix, C.T. papillae, melanin, dermal root sheath.  

Slide 11: Hair follicle, l.s., midregion. h=hair, i=inner root sheath, o=outer root sheath, d=dermal sheath (labels are displaced slightly to the right).  

Slide 12: Hair follicle (cross section). Identify the layers. The hair follicle is of epidermal origin.  

Slide 13: Developing hair (mouse embryo). Follicles growing down into mesenchyme.  

Slide 14: Hair follicle and sebaceous glands. Note that the hair follicles serve as ducts for the sebaceous glands. m = arrector pili muscle, s=sebaceous gland.  

Slide 15: Sebaceous gland.  

Slide 16: Sebaceous gland (rat) Plastic embedded. Note the cellular disintegration (the debris = holocrine secretion).  

Slide 17: Eccrine (merocrine) sweat glands in dermis. Also shows sweat gland duct entering the dermis (also see slide #2).  

Slide 18: Eccrine sweat glands, ducts, Plastic embedded. (Lighter structures = glands; darker = ducts at the periphery of the glands. Dark pink = myoepithelial cells)  

Slide 19: Sweat gland duct spiralling into stratum corneum.  

Slide 20: Human axilla (low power) - has both eccrine and apocrine sweat glands.  

Slide 21: Apocrine glands and ducts (central in field) and eccrine glands and ducts to both sides of the field; also chain follicle with a sebaceous gland.  

Slide 22: Apocrine sweat glands of human axilla. The apocrine glands have much longer lumina and dilated ducts.  

Slide 23: Nail root (longitudinal section). Locate bed, plate, matrix, eponychium.  

Slide 24: Meissner's corpuscle [1], dermis [2], epidermis [3].  

Slide 25: Thick skin with Pacinian corpuscles and sweat glands in and among fat lobules, no clear demarcation between integument and subcutaneous tissue, human finger.


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