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>> Objectives
>> Student Assessment
>> Required Readings
>> Objectives
>> Student Assessment
>> Required Readings


MORPHOLICAL AND DEVELOPMENTAL BASIS OF MEDICINE MODULE

HUMAN GROSS ANATOMY UNIT

Module DIrector
Bruce Ian Bogart, Ph.D.
e-mail: bogarb01@popmail.med.nyu.edu
Department: Cell Biology
Room: MSB 619
Phone: X5237

Objectives of the Human Gross Anatomy Unit:

The immediate objective of the gross anatomy unit is to introduce the medical student to the structural organization of the human body at the macroscopic level. The long-term objective of this course, as well as the curriculum in general, is to provide the student with the tools, time, and place to become an independent, self-motivated learner who can confidently use morphological information (data) to interpret and solve biomedical problems at any point in his or her career. Thus, the faculty wishes to instill in the student the basics of the scientific method as it applies to anatomy; i.e., information (data) gathering (including original observations), synthesis, presentation (effective communication) of pertinent information, and, finally, the use of this information in problem-solving. In addition, we try to do this in a noncompetitive environment that promotes student-student communication and free exchange of information.

The above objectives are met in Gross Anatomy by employing a variety of didactic approaches. Faculty presentations in lectures and small-group conferences/demonstrations not only provide specific information, but also serve as models for how data should be organized and communicated. Students are then trained and encouraged to acquire information on their own while mastering the skills necessary to communicate it and discuss it with others.

This course is organized around the anatomy laboratory as the environment where the student practices the principles described above.

The class is divided into teams of six students who explore anatomy primarily at the dissection table. While two or three students from the team are dissecting, the others are attending a conference or participating in some other learning experience (such as a prosection, radiology presentation, case study discussion, or computer-assisted instruction session). At the end of each period, the entire team of six students meets in the lab for 15 to 30 minutes; the dissectors demonstrate and discuss their laboratory findings, as well as answer questions generated by the other members of the group, which may have arisen in their conferences. After this exchange, the students switch roles. The discussion periods require every student to verbalize the information that he or she has gathered. This process was introduced into the course to foster students' synthesis of information in a non-judgmental environment and to increase communication between these future clinicians.


I. Laboratory Assignments And Scheduling

A. The Dean's office has assigned you to one of four sections (A, B, C 1, C 2 D, or E). Find out your designation as soon as possible, posted on the ground floor Coles corridor bulletin board. (No changes will be allowed in these letter designations.) Sections A B, and C 1 will share dissection tables 1-13 in Coles Lab G06. Sections C 2, D and E will share dissection tables 17-29 in Coles Lab G08.

B. Each dissection table has six or seven students assigned to it. These assignments are posted on the student bulletin board found in Coles Room G07. It is important that each group purchase a Dissector and Atlas BEFORE the first lab for lab use only (section II). The dissection table must also purchase a combination lock for their locker. The combination lock CANNOT be place on the locker before the first lab period. The members of the dissection team should share the cost of these books. Mark your table number clearly on the binder and cover. (You will also want your own clean copy for use outside the laboratory.) Be sure to lock your lab books in your cabinets

Each table will have three pairs of dissectors: Pair X, Pair Y, and Pair Z. These designations, assigned by the faculty, are posted next to each dissection table. Dissection partners are rotated after each major formal examination.

C. It is important that you attend lecture periods, prosections, demonstrations, and conferences at the times designated for your pair and section in order to assure each student the opportunity to attend all scheduled presentations. You are assigned to class sessions according to the X, Y, Z designations. Your specific activities will vary from day to day within each week. Be sure to check your course schedule every day. Your letter designations will also be important for examination seating and will change after each exam period.

D. Each pair of dissectors is assigned one laboratory session in which they are assured of an opportunity to dissect. Each group (six or seven students per table) is responsible for the completed dissection. The faculty will periodically assess each group's progress and make general comments about the quality of the group's efforts. Since you will be dissecting only 1/3 to 1/2 of the time, it is imperative that the group meet at the assigned times to review the dissection. The dissectors are responsible to both the group and to the faculty to discuss and disseminate the information they have obtained concerning their dissection. All members of the lab group are dependent on each other to complete the dissection successfully. Laboratory attendance is required of every member of the group in order to fulfill this obligation.

E. Attendance and participation are required for all case study exercises. Student participation and interaction are necessary for the case study exercises to be a successful learning experience. It would be unprofessional for a student to come unprepared and thereby shift the burden of .????? The faculty member who is leading the case study will verbally assess each student’s participation. This feedback is designed to make sure that the student is working at an acceptable level before the formal examination.


II. Textbooks

Dr. Ort and I will provide you with a series of anatomy notes that represent the core information necessary for this course. We require each student to buy an Anatomy reference text. We suggest that the student purchase Clinically Oriented Anatomy by Moore and Dalley. This book will be very helpful for the case studies. In addition, some students often seek an additional text that stresses fundamental concepts and then use a reference text for the details. Human Structure by Cartmill, Hylander, and Shafland, Harvard U. Press, 1987 is such a text. It presents the fundamental categories of anatomical organization in a coherent, reasonable, and thoughtful manner. You may find it helpful. It is also available in the N.Y.U. Medical Book Store.

B. We require that each table have a copy of Grant's Dissector and Grant's Atlas. These two companion books are required because we feel that the class must proceed with the dissection using a common plan. We have chosen Grant's Dissector since it presents a very successful dissection plan that is reinforced by Grant's Atlas. However, the student should realize that this is little more than a listing of the important structures to be studied and in no way is a substitute for a reference text that develops the material.
Buy these two required books before coming to anatomy lab.

III. Dissection Instruments

Each table needs its own dissection instruments in the laboratory. Your table will be issued dissection instruments, courtesy of the Department of Cell Biology, to be returned at the end of the course. You will have a lockable cabinet with 3 shelves for your dissection group in which you can safely store your supplies and materials. The Department of Cell Biology will also provide gloves at the beginning of the course. Plan to purchase gloves thereafter. Be sure you lock up your tools when you finish dissecting; the staff cannot be responsible for missing boxes of gloves, texts, lab coats, or personal belongings. You will also be given a skull to share. If the skull is not returned at the end of the course, then the members of the table will be expected to pay for the skull.


IV. Attire

A. Name tags issued by the Medical Center should be worn at all times during the course; the more quickly we learn your names, the more helpful we can be in teaching anatomy. Name tags should be worn during case studies.

B. White laboratory coats and scrubs (supplied be the school, not by the department) are to be worn while in the dissection laboratory. Lab coats are to be hung on the hooks at either end of the lab. This is a must. DO NOT LEAVE YOUR LAB COATS IN YOUR LOCKER, ON YOUR DISSECTING TABLE OR ON THE BENCH NEXT TO YOU TABLE. You are to wear a clean lab coat each week.

C. Plastic aprons will be provided weekly. Closed shoes are mandatory to prevent accidents due to dropped instruments.

D. Disposable latex gloves are provided while dissecting. We recommend using gloves to avoid irritation from the embalming fluid.

E. Wash your hands EVERY time you leave the laboratory. Eating and smoking are not permitted in lectures, conferences, model room, demonstrations, or laboratory.

F. Every two dissection tables have their own sink. Your group is required to keep your table, sink area, and chalkboards clean and orderly. IT IS ANOTHER WAY TO SHOW RESPECT FOR THE INDIVIDUALS WHO HAVE DONATED THEIR REMAINS FOR MEDICAL EDUCATION. Our cleaning staff is instructed only to clean the floor of the laboratory and empty the various receptacles.

G. In the laboratory you will find various receptacles: large garbage pails for paper wastes, medium-sized pails for organs, pails at the end of the table for drainage, small pails lined with plastic bags for litter from dissection, and small boxes for all used blades. The purpose for each receptacle is set and not interchangeable. NEVER DISCARD PAPER TOWELS IN ANY RECEPTACLE EXCEPT THE LARGE GARBAGE PAILS.

H. The cadaver shrouds are to be neatly folded when dissecting and never left lying on the floor.

I. A guide to proper use of solutions and general laboratory practices are found at the end of this introduction.

V. Bone Box Assignments

Distribution, at announced times, will proceed as follows:
Each dissection team (table) will receive a bone box for home study. This bone box must be shared equitably and kept in a safe place (preferably group members' dorm rooms) at all times when not in use. In addition, a second bone box is placed in each cabinet for use in the lab. During the Head and Neck segment of the course, the dissection team will also borrow two skulls for study. These must be shared and stored safely.

Human Gross Anatomy Titles In Computer- Assisted Instruction
The anatomy faculty has generated several modules that are available online to support and enhance your learning. These can be found on the NYU Curriculum web page under the Morphological and Developmental Basis of Medicine Courseware . We recommend that you visit this site prior to every dissection lab. The online lab manual will give you dissection information, and support. Lecture videos and additional study units and lecture reviews are also available. In some cases, conferences will require you to review this material prior to the conference.

The Departments of Cell Biology in conjunction with Academic Computing have developed several computer-assisted instruction modules in human gross anatomy. These modules include

Skull module that allows you to dissect and reassemble the skull. This module is available on the Gross Anatomy Web Page.

Meninges module allows you to explore and manipulate the meninges of the neurocranium and the meningeal dural sinuses. This module is available on the Gross Anatomy Web Page.

Orbit module that allows you to explore and .manipulate the orbit and its contents.

In addition the Radiology has joined us in preparing radiology modules that support the radiology lectures and conferences to introduce you to radiology

Anatomical software available via Anatomy Laboratory, Gross Anatomy Home Page or in the Library

1. Human Anatomy has both a dissection and review components. The dissection component should be used in the anatomy lab as an aid. .(Anatomy Lab and Home Page)

2. Beyond Versalius is a self-test dealing with cross-sectional and CT images. After you complete the dissection, you should use the cross-sectional anatomy test. (Anatomy Lab and Home Page)

Student Responsibilities For Case Studies

The case study problem-solving exercises are an important aspect of the course. Attendance and participation are required. If a student does not attend a case study, then the student has to make up the case before the exam.

The case studies are designed to promote faculty-student interactions and increase student-student teaching. The case study sessions also increase academic feedback to the student. If a student cannot participate at an acceptable level during a case study, the faculty will ask the student to participate in a tutorial. Faculty comments (feedback) at the end of these sessions are designed to make sure that the student is working at an acceptable level before the formal examination.

Examinations In Human Gross Anatomy

Prior to every examination, each student is required to take an online open book quiz. This will have approximately 40 questions. The other exercise prior to an examination is our practice laboratory exercise. These exercises are timed self-learning exercises that should be approached as both a self-assessment and a test of your present level of preparation.

B. Practice and formal examinations, both laboratory and written exams, emphasize the regions studied in the laboratory since the previous formal examination period. Faculty proctors will assign all seating for exams.

C. Your performance in this course is evaluated according to the "Pass-Fail" system. We only report a "P" or a "F" to the Recorder's office. The written and laboratory components of the course are graded separately but equally. You must pass both in order to pass the course. You will receive your percentage score for each exam. No student can determine whether he or she has passed or failed the course until all the exams are completed. Your numerical scores will be posted according to individual test number. This information is solely for your own personal information. You are competing against the faculty standard, as expressed in our course and examinations, and not against your fellow students. Helping one another will directly improve both your examination performance and your understanding of anatomy and embryology.

D. The answers to the formal laboratory examination will be posted immediately after the examination is over. You will have access to the exam with the answers after the exam is completed. The formal written answers will not be posted, but you may discuss your test performance (not individual questions) with a faculty member.

E. The examination begins promptly at the hours indicated; you should arrive at your designated examining place 5-10 minutes beforehand to assure time for routine matters of seating, etc. Bring several number 2 pencils and a clipboard to write on! All formal exam periods are about four hours in length (inclusive of both written and laboratory parts). Examinations are to be turned in promptly at the time indicated by the proctor. Exams will typically have questions concerning both units of the Macroscopic Structure And Development Of The Human Body Module


Some Points of Consideration for Our Anatomy Pass-Fail Grading System

1. Rather than encouraging isolated study and competitive individual grading, our course emphasizes a common task (dissection of a cadaver by six students) and learning through discussion (or exchange of information) with colleagues and faculty throughout each day.

2. We de-emphasize examinations, not by giving fewer but by giving more examinations, several of which are self-graded. Within the course we give a total of eight formal examinations: 4 formal written, 4 formal lab. There are four practice lab examinations and four practice online quizzes. In a sense, students begin to take course examinations in stride.

3. Each examination is so structured that any student, with the assumed abilities for which she or he was accepted who works regularly throughout the course, will pass. Passing levels are set up prior to each examination and are not altered by performance curves. (This is fundamental for an effective Pass-Fail system.)

4. Scores are returned to the students but not submitted to the Dean's Office. These % scores do not represent competitive statistics. However, students do interpret them as such out of habit. These scores offer a profile, which indicates whether or not a given student is working up to his or her potential. Scores that fluctuate radically or begin high and consistently decline are considered suspect, whereas scores that attain a solid % range and are maintained or improve are considered "excellent."

5. The written examinations are clinical vignettes that have a strong anatomical component. These questions test your ability to use the anatomical material to solve problems. The lab exam requires identification, knowledge of relationships and other information about the structures dissected since the last exam. The student should realize that the basic science courses contain material that is not discarded after the individual courses are completed. The content of each course is an important resource for problem solving in other settings, i.e., other basic science or clinical science courses. The student must demonstrate mastery of this material to pass the course.

6. If a student's performance "falls off" markedly on any examination to below passing, he or she may be asked to make up that section of the course before being passed. The Dean must approve the scheduling of all make-up courses.


EMBRYOLOGY UNIT SYLLABUS

Unit Directors:
Michael Rindler, Ph.D.
e-mail: rindlm01@med.nyu.edu
Department: Cell Biology
Room: MSB 627,
Phone: X5812

Victoria Ort, Ph.D.
e-mail: ortv01@med.nyu.edu
Department: Cell Biology
Room: MSB 671,
Phone: X5363



The Embryology unit of the Morphological and Developmental Basis of Medicine (MD) is designed to give first year medical students a foundation in the development of the major organ systems and the important congenital malformations associated with them. The temporal organization of the unit and the use of faculty who teach in the Gross Anatomy unit is intended to help students use their knowledge of development to aid in studying human anatomy.

Unit Organization.
The Embryology unit is given in the fall semester. There are seven major divisions:
1) Fertilization and the Early Stages
2) Cardiovascular Embryology
3) Gastrointestinal Embryology
4) Urogenital Embryology
5) Development of the Pharyngeal Arches and Face
6) Development of the Limbs
7) Congenital Malformations.

In order to integrate the Embryology and Anatomy unit material, Embryology will not be given on a fixed time schedule. The number of lectures and conferences per week will vary considerably during the semester. Embryology classes are listed in the MD course schedule as well. Please bear in mind that Embryology is taught in part by faculty who also teach the Anatomy unit. Students should check the schedule to ascertain what subject is being taught at a particular time.


Examinations and Evaluation of Student Performance.
Students receive a single pass/fail evaluation in the MD modulee. This will be based primarily on the student's performance on the examinations and quizzes. Embryology will be one component of each exam. These are scheduled for: Sept. 14 (Fertilization and Early Stages), Oct. 13 (Cardiovascular and Gastrointestinal), Oct. 30 (Hindgut/Urogenital), Dec. 1 (Face/Pharyngeal Arches), and Dec. 18 (Limb/Congenital Malformations). All of the examinations will have essay/case study type questions. In addition, students are expected to take the practice written examinations for each topic, which include embryology questions. These are given online.

The examination questions are designed to test the breadth of knowledge and understanding of the student but by necessity, the exams will cover only a subset of the content of the unit. In general questions are not designed to fool or trick the student. However, some of the questions may require a fairly detailed knowledge of the subject matter.

To successfully complete the Morphological and Developmental Basis of Medicine Course, a student must pass each of the exams. In particular, the Embryology questions on each examination will be compiled as a separate score from the Anatomy questions. Students must have a satisfactory score on the Embryology portion of each examination. This is separate and apart from their score on the Gross Anatomy portions. The unit directors will establish the appropriate criteria for a passing grade for each examination based on the overall class performance and past experience. Student performance on the Anatomy portion of the MD exam is not taken into consideration when determining if remedial work in Embryology is required and vice versa. A quiz (Sept. 7/8) and class participation grades in the small group exercises will also count approximately 5% of the overall unit grade.

In the event that a student should be deemed not to have met the standard for passing the Embryology unit, he/she will be required, subject to approval by the Dean of Students, to take a make-up examination given on or before January 2, 2007. The make-up exam will cover those portions of the unit that the student needs to make up and will be in short essay format. If the overall performance of the student is weak, even if only a single examination make-up is required, the unit directors may require that the make-up examination cover the entire unit.

Examinations are not returned to the students. Scores will be e-mailed to each student individually.


Text Books and Study Guides
Handouts for each embryology topic are provided in this Study Guide. The handouts are in the form of detailed and comprehensive written chapters and are generally a substitute for the corresponding chapters in textbooks. Because color reproductions are so much better than xeroxed black and white figures, drawings or pictures from the textbook are not reproduced in the Study Guide. Instead, the figure numbers are listed in the text. In addition, the web-based version of the Study Guide has the figure links embedded in the text for convenient online use by students. Students are therefore urged to refer to the drawings in the textbook and/or online. Slides from the lectures will be posted on the module web site in most cases.

The recommended textbook is Langman’s Medical Embryology, 10th edition, by T.W. Sadler. It is a paperback available in the bookstore. Because of the limited lecture hours in the course, some subtopics will not be covered thoroughly in lecture. Nonetheless, students will be responsible for the basic information in these areas, which will be reviewed prior to the examinations. The topics are covered in the Study Guide and textbook comprehensively, and study questions emphasizing basic knowledge in these topics are included in the Study Guide. Certain Embryology topics will not be covered as part of the Embryology unit and will not appear on examinations. These include the development of the Nervous System, much of the Skeletal System, and Muscle Tissue. It is anticipated that the student will be introduced to the other topics in later courses like Cellular Basis of Medicine (general principles of development, including growth factor signaling and Hox genes), Foundation for Medicine: Basic Tissues and Neuromuscular (Skeletal and Muscle Tissue) and Foundation for Medicine: Brain and Behavior (Brain and Nervous Tissue).

Students often ask if they may use other textbooks. The Developing Human (now in its 7th edition) by Moore and Persaud is also a textbook that students find helpful. Human Embryology, by William Larsen, is an excellent book with very detailed and accurate information. Students may use this book. These books will be put on reserve in the Medical Library for use as a reference and students are encouraged to examine the drawings, especially if they feel those in Sadler are inadequate. Human Embryology & Developmental Biology, a textbook by B. Carlson, was not popular among the students in the past and is not recommended. In addition, other books will be placed on reserve are for optional additional reading. These include Gilbert, S.F., Developmental Biology and Speroff, L., Glass, R.H., and Kase, N.G. Clinical Gynecologic Endocrinology and Infertility.

Students may wish to test their knowledge of Embryology in preparation for the examinations. The Study Guide and Review Manual of Human Embryology by Moore & Persaud, available in the bookstore, is recommended. Other guides, such as the Embryology Board Review Series may also be of some benefit.


Case Discussions/Small Group Teaching.
Embryology is primarily taught in lecture-conference format. In addition to the small group exercises scheduled for the Early Stages, we will have two case studies, one in the Cardiovascular section, and one on Genital development. The cases will be presented in class as problem-solving exercises and some materials will be distributed to aid in the understanding of the cases and their implications. The rest of the information in the cases will be disclosed in the conferences themselves. Students are encouraged to work with their fellow students in studying the case background material. It is essential that students come to the discussions well prepared, having read the handouts and familiarized themselves with the chapters in the textbook. To encourage adequate preparation, brief quizzes may be given at the beginning of the small group exercises. However, students will be given advance notice if a quiz is to be given. Class participation grades will also be given in some of the small group sessions.

This year most of the cases or small group exercises will be given over two days, with half the class each day. We ask students who have their sessions first not to diminish the experience by sharing detailed information with those whose sections are later that day or the following day.


Review Sessions and Study Questions.
In order to promote student participation in pre-examination discussions and review sessions, a series of Study Questions/Problem Solving Exercises has been prepared for each topic in the unit. These questions will serve as the basis for the Early Stages discussion on Sept. 7/8 and the scheduled pre-exam reviews. Students are urged to come to the sessions prepared to answer the questions and discuss any difficulties they may have with the subject matter. In addition, informal optional review sessions will be held periodically to help students who may need additional support throughout the semester. Currently, one of these review sessions has been schedule for Oct. 6 (Cardiovascular).

The study questions are designed to help students test their knowledge of material and to prepare for exams. Drs. Rindler and Ort will be happy to assist students in answering the study questions. This can be done by e-mail or in person. However, students are not to take advantage of faculty assistance to avoid having to make an effort to answer the study questions on their own.


Computer Programs/Library Materials.
Computer programs are available in several relevant areas and are helpful for learning embryology. Students have found that the Basic Embryology Resource Program (BERP) developed at Univ. of Pennsylvania is very helpful, particularly for the Early Stages and other parts of the unit. The program consists of several modules, some animated, and primarily serve as a visual aid of overall development as well as several of the organ systems. The modules were each developed independently and thus vary greatly in scope and detail. This program is available on the Macintosh computers in the 2nd Floor Coles seminar rooms and CD’s are available on reserve in the library as well. The web site also has other useful visual materials and links to sources of information, such as Clinical Human Embryology. The Simbryo animations that come with the textbook are brightly colored and somewhat useful for embryonic folding (check Fertilization and GI) and GI system development. However, they do lack detail.

In addition, in conjunction with the Advanced Educational Systems here at NYUMC, under the direction of Dr. Martin Nachbar, we have developed computer-assisted, case-based learning programs for both Cardiovascular System and Gastrointestinal System Embryology with special emphasis on clinical diagnosis. Many students liked these programs in the past. They are worthwhile but do require a significant time commitment to complete. Students are urged to try them out and then decide how much time to devote to these programs. They are available through the Embryology web site. If you are using a remote computer, you will need to download Shockwave to run these programs. Links have been set up from the module sites to help you find and download the program through Netscape Navigator. There are also programs on heart development on the Embryology website which you are welcome to use.

Office Hours.
There are no formal office hours but the unit directors are happy to meet with students or answer questions by e-mail. Please contact Dr. Rindler or Dr. Ort to set up a convenient time to meet. Students are also encouraged to contact individual lecturers in specific topics in the unit, especially those teaching Anatomy, to ask questions about course material in their areas. In addition, please feel free to contact the unit directors concerning any general problems that arise.