Case II: Question 11
Zollinger-Ellison Syndrome

Mr. Mann has Zollinger-Ellison Syndrome, a constellation of symptoms consisting of:

  • gastric acid hypersecretion
  • severe peptic ulcer disease
  • gastrin-secreting tumors, usually of the pancreas

    Gastric acid hypersecretion in Z-E Syndrome is caused by:

    TRUE FALSE
    Increased circulating gastrin levels, unopposed by acid feedback inhibition
    Hyperplasia of parietal cells due to the trophic effects of gastrin.
    The secretory effects of gastrin acting on an increased parietal cell mass.

    Educational Computing

    © New York University