H2 Blockers
Histamine interacts with H2-receptors on gastric parietal cells to stimulate acid secretion. The H2 blockers compete with histamine for H2 receptors on the parietal cell but do not stimulate secretion. Cimetidine (Tagamet) is an example.
Click here to see the structure of cimetidine.
Click here to see the structure of non-imidazole H2-receptor antagonists.
Click here to see an animation of cimetidine effects.
Educational Computing
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