Leukotriene Receptors
Leukotrienes signal via Gi and Gq G-protein coupled receptors. Hence they lead to smooth muscle contraction. |
There are two classes of LT receptors
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In the airways, smooth muscle contraction leads to bronchioconstriction.
The allergy and asthma drug montelukast (Singulair) is a cysLT receptor antagonist |