CORE FOUNDATIONS FOR MEDICINE TUTORIAL ON EICOSANOIDS

Lipoxins

Lipoxins mediate the resolution of an inflammatory response
Lipoxins:
  • Block cysLT receptors
    • thereby inhibiting inflammatory leukotriene action
  • Activate lipoxin receptors which act to:
    • inactivate inflammatory cells
    • stimulate phagocytosis of dead cells
    • stimulate proliferation of wound-healing cells

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